Small RNAs Guide Hematopoietic Cell Differentiation and Function

Small RNAs guide hematopoietic cell differentiation and function.

MicroRNAs (miRNAs) are key regulators of gene expression that help direct normal differentiation and malignant transformation of hematopoietic cells. This review summarizes our current knowledge of how miRNAs function in normal and malignant hematopoiesis and how miRNAs might be applied for disease treatment.

Differentiation and Function Small RNAs Guide Hematopoietic Cell

Differentiation and Function of Hematopoietic Cell Surfaces

culturally unbiased enough to be used in community surveys. Leventhal, Nerenz, and Straus then show how individual and social variation in the appraisal of symptoms complicate the neatly objective methods of epidemiology. People's awareness and interpretations of their symptoms can affect the incidence and prevalence rates of many diseases. The authors illustrate their argument with an extensiv...

Small RNAs: classification, biogenesis, and function.

Eukaryotes produce various types of small RNAs of 19-28 nt in length. With rapidly increasing numbers of small RNAs listed in recent years, we have come to realize how widespread their functions are and how diverse the biogenesis pathways have evolved. At the same time, we are beginning to grasp the common features and rules governing the key steps in small RNA pathways. In this review, I will ...

Small Airways Function Declines After Allogeneic Hematopoietic Stem Cell Transplantation

Word count: 218 words) Bronchiolitis obliterans (BO) following allogeneic hematopoietic stem cell transplantation (HSCT) affects peripheral airways. Detection of BO is presently delayed by the low sensitivity of spirometry. We examined the relationship between peripheral airway function and time since HSCT, and compared it with spirometry and clinical indices in 33 clinically stable allogeneic ...